Effects of Resveratrol Against Induced Metabolic Syndrome in Rats: Role of Oxidative Stress, Inflammation, and Insulin Resistance

Table 3

Effect of resveratrol on the serum lipid profile and hemostatic glucose parameters in HFFD-induced MS rats.

Parameters	Experimental groups
	Cont.	MS	Res	MS + Res
TG (mg/dl)	182.78 ± 4.88^c	262.06 ± 9.51^a	183.70 ± 3.71^c	236.01 ± 6.97^b
TC (mg/dl)	182.99 ± 2.46^b	199.20 ± 3.34^a	180.80 ± 2.35^b	185.40 ± 2.50^b
VLDL-c (mg/dl)	36.55 ± 0.98^c	52.41 ± 1.23^a	36.74 ± 0.74^c	47.20 ± 1.39^b
LDL-c (mg/dl)	70.44 ± 4.80^b	86.54 ± 4.79^a	66.86 ± 2.31^b	70.20 ± 3.47^b
HDL-c (mg/dl)	76.00 ± 1.76^a	60.25 ± 1.24^c	77.20 ± 2.52^a	68.00 ± 1.14^b
Glucose (mg/dl)	94.55 ± 3.71^c	141.49 ± 5.01^a	99.45 ± 2.10^c	126.69 ± 3.16^b
Insulin (μIU/ml)	5.37 ± 0.12^c	8.20 ± 0.17^a	5.33 ± 0.18^c	6.80 ± 0.53^b
HOMA-IR	1.21 ± 0.04^c	2.82 ± 0.05^a	1.27 ± 0.03^c	2.18 ± 0.19^b

Values are presented as mean ± SEM for eight rats per group. Means with different superscripts in the same row differ significantly, . Cont.: control; MS: metabolic syndrome; Res: resveratrol; MS + Res: metabolic syndrome + resveratrol. TG: triglyceride; TC: total cholesterol; VLDL-c: very low density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; HDL-c: high-density lipoprotein-cholesterol; HOMA-IR: homeostasis model assessment for insulin resistance.