Cerebral Blood Flow Velocity Modulation and Clinical Efficacy of Acupuncture for Posterior Circulation Infarction Vertigo: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the included studies.

Author, year	Study design	Sample size	Participants		Intervention			Main Outcomes
			Average age (years)	Gender (male/female)	Treatment group	Control group	Course (days)
Dong et al., 2020 [36]	RCT	90	T: 51.4 ± 9.4; C: 52.6 ± 7.7	T: 25/20; C: 27/18	Manual acupuncture Flunarizine hydrochloride	Flunarizine hydrochloride	21	①②③④⑦
Li et al., 2020 [37]	RCT	80	T: 61.53 ± 4.53; C: 62.13 ± 4.57	T: 22/18; C: 21/19	Manual acupuncture Conventional treatment	Conventional treatment	20	⑥⑧
Zhang et al., 2020 [38]	RCT	60	—	—	Manual acupuncture Conventional treatment	Flunarizine hydrochloride Conventional treatment	10	①②③④⑤
Deng et al., 2019 [39]	RCT	60	T: 62.17 ± 9.76; C:62.1 ± 10.17	T: 11/19; C: 12/18	Manual acupuncture Conventional treatment	Conventional treatment	10	①⑤⑧
Dang, 2018 [40]	RCT	69	T:62.26 ± 20.23; C: 61.78 ± 21.57	T: 14/25; C: 11/19	Manual acupuncture Flunarizine hydrochloride Betastatin	Flunarizine hydrochloride Betastatin	10	①⑦
Zhang et al., 2017 [41]	RCT	60	T: 62.40 ± 9.7; C: 61.30 ± 10.1	T: 11/19; C: 10/20	Manual acupuncture Conventional treatment	Flunarizine hydrochloride Conventional treatment	7	①②③④
Zhou et al., 2017 [42]	RCT	60	T: 57.9 ± 12.8; C: 60.4 ± 12.7	T: 23/17; C: 11/9	Manual acupuncture Conventional treatment	Vinpocetine injection Conventional treatment	14	①
Chai, 2016 [43]	RCT	92	T: 56.7 ± 6.1; C: 57.3 ± 6.9	T: 27/19; C: 25/21	Manual acupuncture Flunarizine hydrochloride Conventional treatment	Flunarizine hydrochloride Conventional treatment	20	①②③④⑤⑦
Chen et al., 2016 [44]	RCT	70	All: 49.3 ± 6.5	T: 19/16; C: 17/18	Electroacupuncture Conventional treatment	Conventional treatment	14	①
Geng, 2016 [45]	RCT	70	T: 59.3; C: 61	T: 20/15; C: 17/18	Manual acupuncture Betastatin Danhong injection	Betastatin Danhong injection	14	①②③④
Zhang et al., 2014 [46]	RCT	78	T: 56.86; C: 57.02	T: 17/22; C: 15/24	Electroacupuncture Conventional treatment	Flunarizine hydrochloride Conventional treatment	10	①②③④
Zhou et al., 2014 [47]	RCT	60	All: 54.0 ± 3.8	T: 18/17; C: 15/10	Manual acupuncture Pushen capsule	Pushen capsule	15	①
Cheng et al., 2013 [48]	RCT	72	T: 51.81 ± 5.63; C: 52.17 ± 6.07	T: 13/22; C: 12/25	Manual acupuncture Conventional treatment	Nimodipine Conventional treatment	20	①⑤
Qian et al., 2013 [49]	RCT	98	T: 55.74 ± 5.36; C: 58.63 ± 5.75	T: 26/23; C: 24/25	Manual acupuncture Conventional treatment	Conventional treatment	14	①②③④
Wang, 2013 [50]	RCT	80	T: 45–75; C: 48–77	T: 23/17; C: 20/20	Manual acupuncture Alprostadil injection	Alprostadil injection	14	①
Li et al., 2012 [51]	RCT	112	T: 60.2 ± 8.2; C: 59.1 ± 7.2	T: 29/30; C: 26/27	Manual acupuncture Conventional treatment	Conventional treatment	20	①
Liu et al., 2012 [52]	RCT	71	T: 60.46 ± 8.47; C: 59.83 ± 9.36	T: 18/19; C: 14/20	Electroacupuncture	Flunarizine hydrochloride	42	①②③④
Ma and Zhang, 2012 [53]	RCT	120	T: 60.0 ± 3.4; C: 62.0 ± 2.8	T: 21/39; C: 18/42	Manual acupuncture Gastrodin injection Conventional treatment	Gastrodin injection Conventional treatment	10	①②③④
Luo, 2010 [54]	RCT	61	T: 63.74 ± 16.75; C: 62.98 ± 19.42	T: 20/11; C: 18/12	Manual acupuncture Conventional treatment	Conventional treatment	18	①
Gao and Zhao, 2009 [55]	RCT	78	T: 60.49 ± 4.87; C: 59.89 ± 5.06	T: 24/18; C: 20/16	Manual acupuncture Conventional treatment	Flunarizine hydrochloride Conventional treatment	15	①

T: treatment group; C: control group; ① Clinical Effective Rate; ② blood flow velocity of basilar artery; ③ blood flow velocity of left vertebral artery; ④ blood flow velocity of right vertebral artery; ⑤ Traditional Chinese Medicine Vertigo Symptom Scale; ⑥ Dizziness Handicap Inventory; ⑦ Symptom Scale of Traditional Chinese Medicine; ⑧ Activity of Daily Living.