Systematic Understanding of Mechanism of Danggui Shaoyao San against Ischemic Stroke Using a Network Pharmacology Approach

Table 2

Drug active ingredient-target gene (common targets of six drugs).

Gene	Gene ID
CASP3	836
SOD2	6648
NOS3	4846
HMOX1	3162
MAPK1	5594
F2	2147
MMP2	4313
GSK3B	2932
MAPK8	5599
IL-2	3558
PPARG	5468
NR3C1	2908
MAPK14	1432
REN	5972
F3	2152
IGF-1	3479
BCL2L1	598
PARP1	142
EGFR	1956
CASP7	840
ALB	213
CYP19A1	1588
PPARA	5465
GSR	2936
FABP4	2167
IGF-1R	3480
MMP3	4314
MAOA	4128
NQO1	1728
MMP13	4322
HSP90AA1	3320
CCNA2	890
AKR1C3	8644
MDM2	4193
TGFBR1	7046
CALM1	801
PGR	5241
TGFB2	7042
CYP2C9	1559
ESR1	2099
NR3C2	4306
KDR	3791
GSTP1	2950
F7	2155
AR	367
NR1I2	8856
AURKA	6790
MAP2K1	5604
B2M	567
CASP1	834
HSPA8	3312
MAOB	4129
FGFR1	2260
HSP90AB1	3326
HMGCR	3156
JAK2	3717
MME	4311
CTSB	1508
LCN2	3934
HSD11B1	3290
SRC	6714
XIAP	331
SULT1E1	6783
VDR	7421
GSTA1	2938
GCK	2645
INSR	3643
CDK2	1017
NCOA2	10499
S100A9	6280
FABP5	2171
BMP2	650
TEK	7010
MET	4233
CDK6	1021
CYP2C8	1558
CTSK	1513
PSAP	5660
THRB	7068
PDPK1	5170
ADAM17	6868
KIT	3815
EPHX2	2053
FKBP1A	2280
MMP12	4321
CTSS	1520
MAPK10	5602
FABP3	2170
RARA	5914
MAPKAPK2	9261
PIK3R1	5295
PDE4D	5144
LSS	4047
AKT2	208
PIM1	5292
AKR1B1	231
PLA2G2A	5320
NR1I3	9970
OAT	4942
DUSP6	1848
PGF	5228
CHEK1	1111
ESRRA	2101
PPIA	5478
TNNC1	7134
AKR1C1	1645
GSTM1	2944
HCK	3055
SULT2A1	6822
PDK2	5164
F10	2159
RORA	6095
NR1H3	10062
AKR1C2	1646
EIF4E	1977
BRAF	673
CA2	760
AMD1	262
MMP8	4317
JAK3	3718
NCOA1	8648
NR1H4	9971
THRA	7067
PDE4B	5142
PTPN11	5781
GART	2618
RBP4	5950
PDE5A	8654
BACE1	23621
WAS	7454
GRB2	2885
PTPN1	5770
PROCR	10544
SDS	10993
PPP5C	5536
PRKCQ	5588
BCHE	590
ACADM	34
DHFR	1719
FGFR2	2263
TTR	7276
PYGL	5836
GC	2638
ANXA5	308
CES1	1066
LCK	3932
DPP4	1803
FKBP1B	2281
FABP7	2173
FECH	2235
STS	412
ELANE	1991
BAG1	573
ERBB4	2066
GM2A	2760
TPX2	22974
PLK1	5347
TYMS	7298
DCK	1633
BHMT	635
CTNNA1	1495
CRABP2	1382
ESRRG	2104
RXRA	6256
MTAP	4507
SHBG	6462
NCOA5	57727
PPARD	5467
ABL1	25
TTPA	7274
FKBP3	2287
GRB14	2888
PCTP	58488
CTSF	8722
ADK	132
HSD17B1	3292
KIF11	3832
RFK	55312
FNTB	2342
YARS1	8565
HNMT	3176
BCAT2	587