A Novel Formula Comprising Wolfberry, Figs, White Lentils, Raspberries, and Maca (WFWRM) Induced Antifatigue Effects in a Forced Exercise Mouse Model

Figure 7

Illustration of the antifatigue effect of WFWRM through regulating antifatigue-related biochemical indicators. The WFWRM inhibited mitochondrial lipid peroxidation by increasing antioxidant enzymes (SOD and GSH-PX) and reducing the level of MDA. The downregulation of LDH and LA was responsible for the restraint of antifatigue by restraining the lactic acid shuttle mechanism. The upregulation of storing or mobilizing MG and LG could increase the concentrations of GLU to provide energy directly to antifatigue in the body. The WFWRM could relieve fatigue caused by muscle damage by decreasing the production of CK, reducing protein consumption, and accelerating the metabolism of BUN.