Elucidating the Neuroprotective Effect of Tecoma stans Leaf Extract in STZ-Induced Diabetic Neuropathy
Table 3
Effect of Tecoma stans extract on the grip strength test.
Normal Control
Diabetic Control
Gabapentin 50 mg/kg
TSE 200 mg/kg
TSE 300 mg/kg
TSE 400 mg/kg
TSE 400 mg/kg + Gabapentin
0 Week
124.21 ± 2.21
124.51 ± 2.51
123.85 ± 3.22
128.85 ± 2.76
126.73 ± 1282
124.75 ± 2.6
127.81 ± 2.8
Week 1
125.32 ± 2.51
69.88 ± 4.82
75.35 ± 1.12
74.75 ± 2.74
73.85 ± 2.52 +
79.55 ± 4.40 ,+
74.50 ± 4.25
Week 2
123.85 ± 3.22
52.59 ± 2.25
83.05 ± 5.62
70.72 ± 4.12 ,+
79.69 ± 3.30,++
85.29 ± 4.87 ,+,a
82.11 ± 5.30 ,aa
Week 3
129.73 ± 3.82
35.58 ± 4.92
99.95 ± 6.12
75.25 ± 3.41 ,++
80.15 ± .2.71 ,++
89.09 ± 2.67 ,aa
98.01 ± 4.32 ,aa
Week 4
128.25 ± 3.51
23.58 ± 3.52##
114.38 ± 2.52
84.93 ± 4.51##,,+++
94.88 ± 3.12##,,+
104.75 ± 3.14#,,aa
116.45 ± 3.68 ,aaa
Data are expressed as mean ± SD (n = 6). Data were statistically analyzed using two-way ANOVA followed by Tukey–Kramer’s multiple comparison test at ,, and . The values are expressed as # and ## compared with the normal control group at 4th week; ,, and compared with the diabetic control group; +,++, and +++ compared with standard treatment Gabapentin; and compared with TSE 200 mg/kg.
