The Study of the Transport Mechanism of Isorhynchophylline in Liver

Table 7

IRN content of different groups in the liver tissue and plasma.

Groups	Plasma(mg·mL^−1)			Liver (mg·mL^−1)	Kp value	Kp value (mean)
	90 min	180 min	300 min
Control group 1	0.2438	0.0204	0.0884	0.0336	0.3800	0.3985 ± 0.0472
Control group 2	0.0655	0.1007	0.0418	0.0159	0.3802
Control group 3	0.1327	0.2867	0.0794	0.0299	0.3768
Control group 4	0.5363	0.4693	0.0800	0.0298	0.3727
Control group 5	0.1321	0.0990	0.0304	0.0147	0.4828
Control group 6	0.3526	0.0909	0.0786	—	—
RIF group 1	0.0751	0.2311	0.1862	0.0275	0.1475	0.2859 ± 0.1218
RIF group 2	0.3236	0.0083	0.0679	—	—
RIF group 3	0.0413	0.4281	0.0600	0.0200	0.3340
RIF group 4	0.5044	0.1171	0.0800	0.0301	0.3764
RIF group 5	0.6505	0.0898	0.0109	—	—
RIF group 6	0.1362	0.0616	0.0065	0.0473	—
ADR group 1	0.1111	0.0601	0.0734	0.0365	0.4977	0.1920 ± 0.2038
ADR group 2	0.0700	0.5202	0.0700	0.0064	0.0918
ADR group 3	0.0900	0.2470	0.0043	—	—
ADR group 4	0.0109	0.3578	0.0715	—	—
ADR group 5	0.1910	0.0104	0.0166	0.0098	0.0900
ADR group 6	0.0012	1.9255	0.1615	0.0143	0.0885