Comprehensive Computational Analysis of Honokiol Targets for Cell Cycle Inhibition and Immunotherapy in Metastatic Breast Cancer Stem Cells

Table 1

Potential therapeutic targets of honokiol (PTTH) in metastatic breast cancer stem cells (mBCSCs).

No.	Protein symbol	Protein name	Database
1	CASP9	Caspase 9	STITCH
2	IL4	Interleukin 4	STITCH
3	PDK1	Pyruvate dehydrogenase kinase isoform 1	Swisstargetprediction
4	CCND1	Cyclin D1	STITCH
5	CSF1R	Macrophage colony stimulating factor receptor	Swisstargetprediction
6	TRAP1	Heat shock protein 75 kDa, mitochondrial	Swisstargetprediction
7	VEGFA	Vascular endothelial growth factor A	STITCH
8	HDAC8	Histone deacetylase 8	Swisstargetprediction
9	CAPN1	Calpain 1	STITCH
10	PARP1	Poly (ADP-ribose) polymerase-1	Swisstargetprediction
11	MGLL	Monoglyceride lipase	Swisstargetprediction
12	NQO2	Quinone reductase 2	Swisstargetprediction
13	RXRA	Retinoid X receptor alpha	canSAR Black
14	CNR1	Cannabinoid receptor 1	Swisstargetprediction
15	HSP90AB1	Heat shock protein HSP 90-beta	Swisstargetprediction
16	AURKB	Serine/threonine-protein kinase Aurora-B	Swisstargetprediction
17	PTGER4	Prostanoid EP4 receptor	Swisstargetprediction
18	HSP90AA1	Heat shock protein HSP 90-alpha	Swisstargetprediction
19	DYRK1A	Dual-specificity tyrosine-phosphorylation regulated kinase 1A	Swisstargetprediction
20	GSK3A	Glycogen synthase kinase-3 alpha	Swisstargetprediction
21	ACHE	Acetylcholinesterase	Swisstargetprediction
22	PAK1	Serine/threonine-protein kinase PAK 1	Swisstargetprediction
23	FAAH	Anandamide amidohydrolase	Swisstargetprediction
24	CAPN2	Calpain 2	STITCH
25	CAPN3	Calpain 3	STITCH
26	HDAC1	Histone deacetylase 1	Swisstargetprediction
27	EPHX2	Epoxide hydratase	Swisstargetprediction
28	CDC25B	Dual specificity phosphatase Cdc25B	Swisstargetprediction
29	HDAC6	Histone deacetylase 6	Swisstargetprediction
30	SIRT2	NAD-dependent deacetylase sirtuin 2	Swisstargetprediction