Research Article

Network Pharmacology and In Vivo Analysis of Dahuang-Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis

Figure 11

The levels of endothelial nitric oxide synthase (eNOS), epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF), and interleukin (IL)-6 in kidney tissues from individual rats were measured using ELISA. DHHQD treatment reduced the levels of EGFR and IL-6 in UUO rats. DHHQD treatment increased the levels of eNOS and VEGF in UUO rats. Data are presented as the mean ± SD of each group from three separate experiments. DHHQD-H, Dahuang-Huangqi decoction high dose; DHHQD-L, Dahuang-Huangqi decoction low dose; UUO, unilateral ureteral obstruction. , .
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