Research Article

Network Pharmacology and In Vivo Analysis of Dahuang-Huangqi Decoction Effectiveness in Alleviating Renal Interstitial Fibrosis

Figure 4

Dahuang-Huangqi decoction (DHHQD)-renal interstitial fibrosis (RIF) protein-protein interaction (PPI) network of 30 core protein targets. (a) The PPI network. The colored circles represent 139 targets of the protein ingredients of DHHQD, and the lines represent their interactions, which involve 2,615 mechanisms. The more central a circle in the network, the more relevant is the research mechanism. (b) The top 30 core proteins are ranked from bottom to top.