Research Article

Inhibition of the NLRP3 Inflammasome by a Quercus Serrata Extract and Isolation of the Component Compounds for the Treatment of Arthritis

Table 6

IC50 values pertaining to the inhibitory activity of compounds 1–5 on nitric oxide (NO) production.

CompoundIC50 (μM)

1158.32 ± 2.58
2134.01 ± 2.63
3121.22 ± 6.86
4117.66 ± 2.63
5111.79 ± 2.52
L-NMMA16.85 ± 3.40

L-NMMA, NG-monomethyl-L-arginine monoacetate.