Research Article
Identification of an Amino Acid Metabolism Signature Participating in Immunosuppression in Ovarian Cancer
Figure 6
Development of risk-sensitive drugs to OV patients. (a) and (b) A heatmap presents the top 50 cMap compounds causing opposite transcriptional disturbance to that caused by the median risk (a) and the scatter plot shows their corresponding MoA (b). (c) Comparison of the IC50 levels between the risk groups of 4 drugs from PRISM database. cMap, connective map; MoA, mechanism of action; PRISM, profiling relative inhibition simultaneously in mixtures.
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