Botanical from the Fruits Mesocarp of Raphia vinifera Displays Antiproliferative Activity and Is Harmless as Evidenced by Toxicological Assessments

Table 7

Effect of RVM on biochemical parameters (ALT, AST, total proteins, and alkaline phosphatase) of the rats during subchronic toxicity study.

Sexes	Parameters	Control	Extract doses (mg/kg)
			250	500	1000
Female	ALT	69.69 ± 1.13^c	57.88 ± 0.71^a	66.63 ± 1.43^b	65.53 ± 0.84^b
	AST	98.88 ± 2.14^c	85.31 ± 3.39^b	74.38 ± 3.27^a	86.63 ± 1.89^b
	T. proteins	11.14 ± 0.31^c	8.80 ± 0.29^a	9.29 ± 0.46^a,b	9.90 ± 0.36^b
	PAL	358.42 ± 7.52^d	342.46 ± 2.30^c	324.67 ± 3.94^b	281.35 ± 4.80^a
Male	ALT	67.72 ± 1.31^b	62.47 ± 1.31^a	69.03 ± 1.80^b	69.25 ± 2.47^b
	AST	103.69 ± 5.37^b,c	87.94 ± 1.52^a	101.50 ± 5.72^b	109.38 ± 1.24^c
	T. proteins	11.31 ± 1.07^b	9.31 ± 0.82^a	9.59 ± 1.09^a	9.95 ± 0.52^a,b
	PAL	438.22 ± 5.65^d	417.70 ± 2.98^c	396.26 ± 4.80^b	317.83 ± 5.65^a

The table values are presented as mean ± standard deviation of 4 repetitions. In the same line and by sex, the values bearing the different letters are significantly different according to Waller Duncan’s multiple comparison test (). Indicators: ALT: alanine aminotransferase, AST: aspartate aminotransaminase; T. proteins: total proteins, ALP: alkaline phosphatase.