Curcumin Prevents Diabetic Osteoporosis through Promoting Osteogenesis and Angiogenesis Coupling via NF-κB Signaling

Figure 2

Cur recovered HG-impaired proangiogenic ability of BMSCs. Endothelial cells stimulated with conditioned medium (CM) from BMSCs treated with NG, HG, and HG + Cur. (a)–(b) Proliferation was determined by EDU555 staining. (c)–(d) Endothelial cell motility in each group was evaluated using the scratch wound assay. (e)–(g) Representative images (e) and quantification of tube formation (f)–(g) were assessed in each group. Data are presented as the mean ± SD from at least three independent experiments. and versus NG group. ^# and ^## versus HG group.

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