Exploring the Ferroptosis Mechanism of Zhilong Huoxue Tongyu Capsule for the Treatment of Intracerebral Hemorrhage Based on Network Pharmacology and <i>In Vivo</i> Validation

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr class="thead"><td class="align_left">ID</td><td class="align_center">MolID</td><td class="align_center">Compound</td><td class="align_center">Degree</td><td class="align_center">BetweennessCentrality</td><td class="align_center">ClosenessCentrality</td></tr><tr><td class="thead-hr" colspan="6"><hr/></td></tr><tr><td class="align_left">HQ7</td><td class="align_center">MOL000098</td><td class="align_center">Quercetin</td><td class="align_center">18</td><td class="align_center">0.23778696</td><td class="align_center">0.51239669</td></tr><tr><td class="align_left">SZ</td><td class="align_center"> </td><td class="align_center">Crocetin</td><td class="align_center">6</td><td class="align_center">0.08568377</td><td class="align_center">0.41059603</td></tr><tr><td class="align_left">HQ6</td><td class="align_center">MOL000422</td><td class="align_center">Kaempferol</td><td class="align_center">6</td><td class="align_center">0.01941172</td><td class="align_center">0.41059603</td></tr><tr><td class="align_left">A</td><td class="align_center">MOL000358</td><td class="align_center">Beta-sitosterol</td><td class="align_center">4</td><td class="align_center">0.01428604</td><td class="align_center">0.40522876</td></tr><tr><td class="align_left">HQ16</td><td class="align_center">MOL000392</td><td class="align_center">Formononetin</td><td class="align_center">3</td><td class="align_center">0.00604758</td><td class="align_center">0.38509317</td></tr><tr><td class="align_left">HQ10</td><td class="align_center">MOL000354</td><td class="align_center">Isorhamnetin</td><td class="align_center">3</td><td class="align_center">0.00570997</td><td class="align_center">0.38509317</td></tr><tr class="table-tr"><td colspan="6"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Top 6 active ingredients of ZL capsule in above related 11 pathways.</div>

Evidence-Based Complementary and Alternative Medicine

tab5

Table 5

Table 5: Exploring the Ferroptosis Mechanism of Zhilong Huoxue Tongyu Capsule for the Treatment of Intracerebral Hemorrhage Based on Network Pharmacology and <i>In Vivo</i> Validation 

Table 5 | Exploring the Ferroptosis Mechanism of Zhilong Huoxue Tongyu Capsule for the Treatment of Intracerebral Hemorrhage Based on Network Pharmacology and In Vivo Validation 