Exploring the Ferroptosis Mechanism of Zhilong Huoxue Tongyu Capsule for the Treatment of Intracerebral Hemorrhage Based on Network Pharmacology and <i>In Vivo</i> Validation

<table class="table-group" id="tab6"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td class="align_left">Targets</td><td class="align_center">Degree</td><td class="align_center">BetweennessCentrality</td><td class="align_center">ClosenessCentrality</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td class="align_left">PTGS2</td><td class="align_center">24</td><td class="align_center">0.44995211</td><td class="align_center">0.55357143</td></tr><tr><td class="align_left">RELA</td><td class="align_center">10</td><td class="align_center">0.04458046</td><td class="align_center">0.41891892</td></tr><tr><td class="align_left">JUN</td><td class="align_center">9</td><td class="align_center">0.03443671</td><td class="align_center">0.41333333</td></tr><tr><td class="align_left">TP53</td><td class="align_center">8</td><td class="align_center">0.068708</td><td class="align_center">0.43055556</td></tr><tr><td class="align_left">TNF</td><td class="align_center">8</td><td class="align_center">0.04903199</td><td class="align_center">0.42465753</td></tr><tr><td class="align_left">CASP8</td><td class="align_center">8</td><td class="align_center">0.03937065</td><td class="align_center">0.41333333</td></tr><tr><td class="align_left">GSK3B</td><td class="align_center">8</td><td class="align_center">0.05341178</td><td class="align_center">0.38271605</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Top 7 targets of ZL capsule in above 11 pathways.</div>

Evidence-Based Complementary and Alternative Medicine

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Table 6

Table 6: Exploring the Ferroptosis Mechanism of Zhilong Huoxue Tongyu Capsule for the Treatment of Intracerebral Hemorrhage Based on Network Pharmacology and <i>In Vivo</i> Validation 

Table 6 | Exploring the Ferroptosis Mechanism of Zhilong Huoxue Tongyu Capsule for the Treatment of Intracerebral Hemorrhage Based on Network Pharmacology and In Vivo Validation 