|
| Category | Term | Count | value | FDR |
|
| GOTERM_BP_DIRECT | GO:0038128∼ERBB2 signaling pathway | 13 | 1.28E − 22 | 9.55E − 20 |
| KEGG_PATHWAY | hsa04012:ErbB signaling pathway | 17 | 1.27E − 20 | 1.01E − 18 |
| GOTERM_BP_DIRECT | GO:0007173∼epidermal growth factor receptor signaling pathway | 12 | 3.15E − 18 | 1.17E − 15 |
| KEGG_PATHWAY | hsa05211:renal cell carcinoma | 14 | 3.40E − 17 | 1.34E − 15 |
| KEGG_PATHWAY | hsa05200:pathways in cancer | 22 | 7.81E − 16 | 2.06E − 14 |
| KEGG_PATHWAY | hsa05205:proteoglycans in cancer | 17 | 1.23E − 14 | 2.43E − 13 |
| GOTERM_BP_DIRECT | GO:0048015∼phosphatidylinositol-mediated signaling | 11 | 2.78E − 13 | 6.89E − 11 |
| GOTERM_CC_DIRECT | GO:0005829∼cytosol | 32 | 7.05E − 13 | 7.90E − 11 |
| GOTERM_BP_DIRECT | GO:0014066∼regulation of phosphatidylinositol 3-kinase signaling | 10 | 7.39E − 13 | 1.38E − 10 |
| GOTERM_MF_DIRECT | GO:0005515∼protein binding | 47 | 1.96E − 12 | 2.97E − 10 |
| KEGG_PATHWAY | hsa04722:neurotrophin signaling pathway | 13 | 3.24E − 12 | 5.11E − 11 |
| GOTERM_MF_DIRECT | GO:0046934∼phosphatidylinositol-4,5-bisphosphate 3-kinase activity | 9 | 5.83E − 12 | 4.43E − 10 |
| KEGG_PATHWAY | hsa05220:chronic myeloid leukemia | 11 | 9.33E − 12 | 1.23E − 10 |
| KEGG_PATHWAY | hsa05223:nonsmall cell lung cancer | 10 | 2.91E − 11 | 3.29E − 10 |
| GOTERM_MF_DIRECT | GO:0004713∼protein tyrosine kinase activity | 10 | 9.41E − 11 | 4.77E − 09 |
| GOTERM_BP_DIRECT | GO:0046854∼phosphatidylinositol phosphorylation | 9 | 1.87E − 10 | 2.79E − 08 |
| GOTERM_BP_DIRECT | GO:0018108∼peptidyl-tyrosine phosphorylation | 10 | 3.46E − 10 | 4.30E − 08 |
| KEGG_PATHWAY | hsa04910:insulin signaling pathway | 12 | 3.57E − 10 | 3.53E − 09 |
| GOTERM_BP_DIRECT | GO:0042059∼negative regulation of epidermal growth factor receptor signaling pathway | 7 | 6.31E − 10 | 6.72E − 08 |
| KEGG_PATHWAY | hsa05100:bacterial invasion of epithelial cells | 10 | 6.37E − 10 | 5.59E − 09 |
| KEGG_PATHWAY | hsa04510:focal adhesion | 13 | 1.90E − 09 | 1.50E − 08 |
| KEGG_PATHWAY | hsa04066:HIF-1 signaling pathway | 10 | 4.19E − 09 | 3.01E − 08 |
| KEGG_PATHWAY | hsa04014:Ras signaling pathway | 13 | 5.47E − 09 | 3.60E − 08 |
| GOTERM_BP_DIRECT | GO:2000145∼regulation of cell motility | 6 | 1.29E − 08 | 1.20E − 06 |
| GOTERM_MF_DIRECT | GO:0019903∼protein phosphatase binding | 7 | 2.02E − 08 | 6.58E − 07 |
| KEGG_PATHWAY | hsa05213:endometrial cancer | 8 | 2.05E − 08 | 1.24E − 07 |
| GOTERM_MF_DIRECT | GO:0005154∼epidermal growth factor receptor binding | 6 | 2.16E − 08 | 6.58E − 07 |
| GOTERM_MF_DIRECT | GO:0005088∼Ras guanyl-nucleotide exchange factor activity | 8 | 2.84E − 08 | 7.20E − 07 |
| GOTERM_BP_DIRECT | GO:0043547∼positive regulation of GTPase activity | 13 | 3.34E − 08 | 2.76E − 06 |
| GOTERM_BP_DIRECT | GO:0000165∼MAPK cascade | 10 | 3.88E − 08 | 2.89E − 06 |
| KEGG_PATHWAY | hsa05215:prostate cancer | 9 | 4.30E − 08 | 2.43E − 07 |
| GOTERM_BP_DIRECT | GO:0007165∼signal transduction | 17 | 4.78E − 08 | 3.24E − 06 |
| GOTERM_BP_DIRECT | GO:0042060∼wound healing | 7 | 8.88E − 08 | 5.51E − 06 |
| KEGG_PATHWAY | hsa05230:central carbon metabolism in cancer | 8 | 9.01E − 08 | 4.74E − 07 |
| KEGG_PATHWAY | hsa05214:glioma | 8 | 1.00E − 07 | 4.96E − 07 |
| GOTERM_BP_DIRECT | GO:0007169∼transmembrane receptor protein tyrosine kinase signaling pathway | 7 | 2.65E − 07 | 1.52E − 05 |
| GOTERM_MF_DIRECT | GO:0017124∼SH3 domain binding | 7 | 9.17E − 07 | 1.99E − 05 |
| GOTERM_BP_DIRECT | GO:0071364∼cellular response to epidermal growth factor stimulus | 5 | 2.08E − 06 | 1.11E − 04 |
| GOTERM_BP_DIRECT | GO:0008286∼insulin receptor signaling pathway | 6 | 2.50E − 06 | 1.24E − 04 |
| GOTERM_BP_DIRECT | GO:0001525∼angiogenesis | 8 | 2.65E − 06 | 1.24E − 04 |
| GOTERM_BP_DIRECT | GO:0007175∼negative regulation of epidermal growth factor-activated receptor activity | 4 | 3.34E − 06 | 1.46E − 04 |
| GOTERM_MF_DIRECT | GO:0004714∼transmembrane receptor protein tyrosine kinase activity | 5 | 3.63E − 06 | 6.90E − 05 |
| GOTERM_MF_DIRECT | GO:0046982∼protein heterodimerization activity | 10 | 4.54E − 06 | 7.67E − 05 |
| GOTERM_MF_DIRECT | GO:0001784∼phosphotyrosine binding | 4 | 5.67E − 06 | 8.62E − 05 |
| KEGG_PATHWAY | hsa05206:MicroRNAs in cancer | 11 | 5.95E − 06 | 2.76E − 05 |
| GOTERM_BP_DIRECT | GO:0000186∼activation of MAPKK activity | 5 | 8.06E − 06 | 3.34E − 04 |
| GOTERM_MF_DIRECT | GO:0019901∼protein kinase binding | 9 | 8.27E − 06 | 1.14E − 04 |
| GOTERM_BP_DIRECT | GO:0000187∼activation of MAPK activity | 6 | 1.19E − 05 | 4.65E − 04 |
| KEGG_PATHWAY | hsa04062:chemokine signaling pathway | 9 | 1.32E − 05 | 5.79E − 05 |
| GOTERM_CC_DIRECT | GO:0045121∼membrane raft | 7 | 1.42E − 05 | 7.93E − 04 |
| GOTERM_MF_DIRECT | GO:0005070∼SH3/SH2 adaptor activity | 5 | 1.74E − 05 | 2.21E − 04 |
| GOTERM_BP_DIRECT | GO:0043065∼positive regulation of apoptotic process | 8 | 1.85E − 05 | 6.88E − 04 |
| GOTERM_BP_DIRECT | GO:0050900∼leukocyte migration | 6 | 2.24E − 05 | 7.67E − 04 |
| GOTERM_BP_DIRECT | GO:0001892∼embryonic placenta development | 4 | 2.27E − 05 | 7.67E − 04 |
| KEGG_PATHWAY | hsa04915:estrogen signaling pathway | 7 | 2.63E − 05 | 1.09E − 04 |
| KEGG_PATHWAY | hsa05231:choline metabolism in cancer | 7 | 2.95E − 05 | 1.14E − 04 |
| KEGG_PATHWAY | hsa04151:PI3K-Akt signaling pathway | 11 | 3.08E − 05 | 1.14E − 04 |
| KEGG_PATHWAY | hsa04015:Rap1 signaling pathway | 9 | 3.19E − 05 | 1.14E − 04 |
| GOTERM_MF_DIRECT | GO:0042802∼identical protein binding | 11 | 3.24E − 05 | 3.79E − 04 |
| KEGG_PATHWAY | hsa05212:pancreatic cancer | 6 | 4.19E − 05 | 1.44E − 04 |
| GOTERM_MF_DIRECT | GO:0046875∼ephrin receptor binding | 4 | 5.03E − 05 | 5.46E − 04 |
| KEGG_PATHWAY | hsa05218:melanoma | 6 | 6.42E − 05 | 2.03E − 04 |
| KEGG_PATHWAY | hsa04917:prolactin signaling pathway | 6 | 6.42E − 05 | 2.03E − 04 |
| GOTERM_BP_DIRECT | GO:0008283∼cell proliferation | 8 | 6.55E − 05 | 0.002121606 |
| GOTERM_CC_DIRECT | GO:0005886∼plasma membrane | 24 | 6.61E − 05 | 0.002469141 |
| GOTERM_BP_DIRECT | GO:0072656∼maintenance of protein location in mitochondrion | 3 | 7.63E − 05 | 0.002367512 |
| GOTERM_MF_DIRECT | GO:0005168∼neurotrophin TRKA receptor binding | 3 | 1.13E − 04 | 0.001145089 |
| GOTERM_CC_DIRECT | GO:0005737∼cytoplasm | 27 | 1.13E − 04 | 0.003168298 |
| GOTERM_BP_DIRECT | GO:0043619∼regulation of transcription from RNA polymerase II promoter in response to oxidative stress | 3 | 1.14E − 04 | 0.003272239 |
| GOTERM_BP_DIRECT | GO:0072655∼establishment of protein localization to mitochondrion | 3 | 1.14E − 04 | 0.003272239 |
| GOTERM_BP_DIRECT | GO:0071902∼positive regulation of protein serine/threonine kinase activity | 4 | 1.26E − 04 | 0.003485245 |
| KEGG_PATHWAY | hsa04068:FoxO signaling pathway | 7 | 1.44E − 04 | 4.38E − 04 |
| GOTERM_BP_DIRECT | GO:0007507∼heart development | 6 | 1.54E − 04 | 0.004099115 |
| GOTERM_MF_DIRECT | GO:0030235∼nitric-oxide synthase regulator activity | 3 | 2.10E − 04 | 0.001949528 |
| GOTERM_CC_DIRECT | GO:0005634∼nucleus | 27 | 2.18E − 04 | 0.004872016 |
| GOTERM_MF_DIRECT | GO:0030971∼receptor tyrosine kinase binding | 4 | 2.31E − 04 | 0.001949528 |
| GOTERM_MF_DIRECT | GO:0016303∼1-phosphatidylinositol-3-kinase activity | 4 | 2.31E − 04 | 0.001949528 |
| KEGG_PATHWAY | hsa04810:regulation of actin cytoskeleton | 8 | 2.43E − 04 | 7.11E − 04 |
| GOTERM_BP_DIRECT | GO:0043066∼negative regulation of apoptotic process | 8 | 2.52E − 04 | 0.006477735 |
| GOTERM_MF_DIRECT | GO:0036312∼phosphatidylinositol 3-kinase regulatory subunit binding | 3 | 2.70E − 04 | 0.002158104 |
| GOTERM_BP_DIRECT | GO:0045741∼positive regulation of epidermal growth factor-activated receptor activity | 3 | 2.73E − 04 | 0.006769871 |
| GOTERM_BP_DIRECT | GO:0045944∼positive regulation of transcription from RNA polymerase II promoter | 11 | 3.16E − 04 | 0.007600594 |
| KEGG_PATHWAY | hsa04660:T cell receptor signaling pathway | 6 | 3.26E − 04 | 9.20E − 04 |
| GOTERM_MF_DIRECT | GO:0004716∼receptor signaling protein tyrosine kinase activity | 3 | 3.37E − 04 | 0.002558199 |
| GOTERM_BP_DIRECT | GO:0036092∼phosphatidylinositol-3-phosphate biosynthetic process | 4 | 3.46E − 04 | 0.008053746 |
| GOTERM_BP_DIRECT | GO:0007266∼Rho protein signal transduction | 4 | 3.67E − 04 | 0.008291918 |
| GOTERM_MF_DIRECT | GO:0043560∼insulin receptor substrate binding | 3 | 4.11E − 04 | 0.002972513 |
| KEGG_PATHWAY | hsa04010:MAPK signaling pathway | 8 | 7.50E − 04 | 0.002042501 |
| KEGG_PATHWAY | hsa04650:natural killer cell mediated cytotoxicity | 6 | 8.13E − 04 | 0.002141603 |
| GOTERM_MF_DIRECT | GO:0005096∼GTPase activator activity | 6 | 0.001034663 | 0.00714858 |
| KEGG_PATHWAY | hsa05160:hepatitis C | 6 | 0.001200247 | 0.003058693 |
| KEGG_PATHWAY | hsa04973:carbohydrate digestion and absorption | 4 | 0.002059125 | 0.005083466 |
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