Research Article

Network Pharmacology Analysis, Molecular Docking, and In Vitro Verification Reveal the Action Mechanism of Prunella vulgaris L. in Treating Breast Cancer

Table 2

Binding energy between quercetin and the top 10 targets in the PPI network.

ReceptorPub IDBinding energy/kcal·mol−1Basic binding energy/kcal·mol−1

ERBB33kex−9.1−7.56
INSR2hr7−7.3−6.97
MET2rfs−8.2−7.84
NCOA12c52−5.8−5.51
NCOA25egv−4.8−4.42
COL3A16fzw−6.6−6.31
TOP2A4r1f−8.4−7.12
DUOX2AF−8−7.24
MAP2AF−6−5.62
SCN5A6lqa−7.8−7.31