Study on the Mechanism of Üstikuddus Sherbiti in Ischemic Cerebrovascular Diseases: Based on Network Pharmacology

Table 3

Docking score of the selected molecules for docking in the binding site of PIK3CA, PIK3RI, AKT1, MAPK1, MAPK3, MEK1, MEK2, NF-κB1A, IKKβ, and mTOR proteins.

Legend receptor docking score (ΔG, kcal/mol)
Legend receptor	PIK3CA	PIK3RI	AKT1	AKT1I	MAPK1	MAPK3	mTOR	MEK1	MEK2	NF-κB1A	IKKβ
PDB ID	6OAC	5UBT	3OCB	3MVH	4CFE	4QTB	4DRI	3WIG	1S9I	1SVC	4KIK
Baicalein	−8.169	−7.94	−6.977	−5.591	−7.003	−6.274	−7.923	−9.682	−6.57	−3.33	−9.09
Kaempferide	−6.965	−8.251	−6.612	−7.074	−6.979	−6.127	−7.584	−8.611	−6.124		−10.012
Kaempferol	−11.174	−10.334	−6.179	−7.138	−6.995	−6.201	−8.101	−10.606	−10.038	−3.788	−10.044
Luteolin	−9.923	−11.827	−8.272	−6.495	−7.161	−6.323	−7.918	−11.405	−7.747	−5.29	−11.335
Naringenin	−8.491	−9.383	−6.571	−6.342	−7.316	−6.516	−8.047	−10.492	−7.82		−8.047
Quercetin	−10.365	−12.24	−7.74	−7.986	−6.849	−6.525	−7.237	−11.572	7.384	−5.684	−11.547