Chinese Herbal Medicine as an Adjunctive Therapy Improves the Survival Rate of Patients with Ischemic Heart Disease: A Nationwide Population-Based Cohort Study

Table 6

Incidence rates, hazard ratio, and confidence intervals of mortality for with and without CHM used anomaly patients in the stratification by gender, age, baseline comorbidity, and Charlson comorbidity index.

Variables	Ischemic heart disease patients						Crude HR	Adjusted HR
	Non-CHM user (N = 20192)			CHM user (N = 20192)
	Event	Person-years	IR^†	Event	Person-years	IR^†	(95% CI)	(95% CI)^‡
Sex
Female	983	51471	19.1	513	66613	7.70	0.40 (0.36, 0.44)	0.46 (0.41, 0.51)
Male	1762	77352	22.8	981	98565	9.95	0.43 (0.40, 0.47)	0.45 (0.41, 0.48)
Age
18–39	31	6460	4.80	11	7248	1.52	0.32 (0.16, 0.63)	0.41 (0.21, 0.83)
40–64	634	66699	9.51	191	76927	2.48	0.26 (0.22, 0.31)	0.32 (0.27, 0.37)
More than 65	2080	55665	37.4	1292	81004	16.0	0.42 (0.39, 0.45)	0.48 (0.45, 0.51)
Baseline comorbidity
No	1568	1077048	14.7	1145	144550	7.92	0.53 (0.49, 0.57)	0.47 (0.43, 0.51)
Yes	1177	21776	54.1	349	20629	16.9	0.32 (0.28, 0.36)	0.31 (0.27, 0.34)
Charlson comorbidity index
0	994	93509	10.6	848	128473	6.60	0.60 (0.55, 0.66)	0.54 (0.49, 0.59)
1	686	20412	33.6	380	25505	14.9	0.43 (0.38, 0.48)	0.41 (0.36, 0.47)
2	410	7245	56.6	133	6323	21.0	0.37 (0.30, 0.45)	0.37 (0.30, 0.45)
3+	655	7657	85.5	133	4877	27.3	0.33 (0.28, 0.40)	0.32 (0.26, 0.38)

IR, incidence rates, per 1,000 person-years; HR, hazard ratio; CI, confidence interval ^†adjusted for CHM used, age, gender, baseline comorbidity, and Charlson comorbidity index in Cox proportional hazards regression ; ; .