|
| Core targets | Protein name | UniProt ID |
|
| AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 |
| VEGFA | Vascular endothelial growth factor A | P15692 |
| MAPK3 | Mitogen-activated protein kinase 3 | P27361 |
| TNF | Tumor necrosis factor | P01375 |
| EGFR | Epidermal growth factor receptor | P00533 |
| SRC | Proto-oncogene tyrosine-protein kinase Src | P12931 |
| PTGS2 | Prostaglandin G/H synthase 2 | P35354 |
| MMP9 | Matrix metalloproteinase-9 | P14780 |
| JUN | Transcription factor AP-1 | P05412 |
| ESR1 | Estrogen receptor | P03372 |
| KDR | Vascular endothelial growth factor receptor 2 | P35968 |
| PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | P42336 |
| AR | Androgen receptor | P10275 |
| MDM2 | E3 ubiquitin-protein ligase Mdm2 | Q00987 |
| MMP2 | 72 kDa type IV collagenase | P08253 |
| APP | Amyloid-beta precursor protein | P05067 |
| PPARG | Peroxisome proliferator-activated receptor gamma | P37231 |
| BCL2L1 | Bcl-2-like protein 1 | Q07817 |
| ACE | Angiotensin-converting enzyme | P12821 |
| IGF1R | Insulin-like growth factor 1 receptor | P08069 |
| PGR | Progesterone receptor | P06401 |
| SERPINE1 | Plasminogen activator inhibitor 1 | P05121 |
| F2 | Coagulation factor II | P00734 |
| MPO | Myeloperoxidase | P05164 |
| NR3C1 | Nuclear receptor subfamily 3 group C member 1 | P04150 |
| MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Q07820 |
| PLG | Plasminogen | P00747 |
| AGTR1 | Type-1 angiotensin II receptor | P30556 |
| CYP19A1 | Cytochrome P450 19A1 | P11511 |
| IGFBP3 | Insulin-like growth factor-binding protein 3 | P17936 |
| AHR | Aryl hydrocarbon receptor | P35869 |
| PGF | Placenta growth factor | P49763 |
| ABCB1 | ATP-dependent translocase ABCB1 | P08183 |
| PTPN1 | Tyrosine-protein phosphatase nonreceptor type 1 | P18031 |
| PPARA | Peroxisome proliferator-activated receptor alpha | Q07869 |
| ACHE | Acetylcholinesterase | P22303 |
| PLA2G4A | Cytosolic phospholipase A2 | P47712 |
| MMP3 | Stromelysin-1 | P08254 |
| PLA2G1B | Phospholipase A2 | P04054 |
| ALOX5 | Polyunsaturated fatty acid 5-lipoxygenase | P09917 |
| TERT | Telomerase reverse transcriptase | O14746 |
| F3 | Coagulation factor III | P13726 |
| CNR1 | Cannabinoid receptor 1 | P21554 |
| NOX4 | NADPH oxidase 4 | Q9NPH5 |
| MMP8 | Matrix metalloproteinase-8 | P22894 |
| NOS2 | Nitric oxide synthase | P35228 |
| AKR1B1 | Aldo-keto reductase family 1 member B1 | P15121 |
| PTGER3 | Prostaglandin E2 receptor EP3 subtype | P43115 |
| ENSG00000196689 | none | none |
| FABP4 | Fatty acid-binding protein 4 | P15090 |
| NLRP3 | NACHT, LRR, and PYD domains-containing protein 3 | Q96P20 |
| PDE4A | cAMP-specific 3′,5′-cyclic phosphodiesterase 4A | P27815 |
| RARB | Retinoic acid receptor beta | P10826 |
|
