Efficacy of Acacia nilotica Linn. Pod’s Sitz Bath plus Vaginal Pessary in Syndromic Management of Abnormal Vaginal Discharge: A Randomized Controlled Trial
Table 3
Microbiological evaluation in the Acacia and placebo groups.
Investigation
Acacia group (n = 33)
value
Placebo group (n = 33)
value
Day 0
Day 11–14
Day 0
Day 11-14
Amsel’s criteria
Whiff test
0.02
1.00
Negative
24 (72.72)
31 (93.93)
25 (75.75)
25 (75.75)
Positive
9 (27.27)
2 (6.06)
8 (24.24)
8 (24.24)
Clue cells
0.02
1
Negative
24 (72.72)
31 (93.93)
24 (72.72)
24(72.72)
Positive
9 (27.27)
2 (6.06)
9 (27.27)
9 (27.27)
Vaginal pH
4.54 ± 0.46
3.93 ± 0.48a
<0.0001
4.57 ± 0.47
4.59 ± 0.44b
0.78
Vaginal wet mount test for microscopic investigation of vaginal discharge
KOH slide for hyphae
1.00
1.00
Present
0 (0)
0 (0)
1 (3.03)
1 (3.03)
Absent
33 (100)
33 (100)
32 (96.96)
32 (96.96)
Normal saline test for trichomonas
1.00
1.00
Absent
33 (100)
33 (100)
33 (100)
33( 100)
Present
0
0
0
0
Pus cells (hpf)
<0.001
0.93
<10
3 (9.09)
24 (72.72)
5 (15.15)
5 (15.15)
11–20
6 (18.18)
6 (18.18)
8 (24.24)
7 (21.21)
21–30
21 (63.63)
2 (6.06)
15 (45.45)
14 (42.42)
>30
3 (9.09)
1 (3.03)
5 (15.15)
7 (21.21)
Pus cells (hpf)
22.96 ± 8.48
8.21 ± 7.85
<0.001
23.15 ± 7.32
22.15 ± 8.7
0.47
Pap smear
Normal
4 (12.12)
20 (60.60)
<0.001
4 (12.12)
8 (24.24)
0.63
Inflammatory
22 (66.66)
11 (33.33)
22 (66.66)
18 (54.54)
BV
7 (21.21)
2 (6.06)
6 (18.18)
6 (18.18)
Candidiasis
0(0)
0(0)a
1 (3.03)
1(3.03)b
Data presented were as follows: no (%) or mean ± SD; aP < 0.0001 considered extremely significant on day 11 from day 0 in the Acacia group; bP > 0.05 considered not significant on day 11 from day 0 in the Placebo group; Tests used were as follows: fisher’s exact test and Wilcoxon matched paired test.
