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S. No | Propolis form | Experimental model | Main results | References |
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1 | Propolis ointment | Square skin incision | Affect stimulating keratinocytes cell proliferation | [30] |
2 | Diabetic foot ulcer | Reduced ulcer area enhanced wound healing | [31] |
3 | Pulp wound | Maintain low inflammation and microbial cell population stimulating restorative dentin | [32] |
4 | Burn | Stimulates the accumulation of glycosaminoglycans on the wound surface required for granulation, tissue growth and wound closure to accelerate the repair of burn tissue | [33] |
5 | Chronic wound | Treatment of chronic wound infection caused by Proteus mirabilis | [34] |
6 | Cell CRL-7522 | Enhance the proliferation, activation and growth of skin cells | [35] |
7 | Rat skin wound | Speed up wound healing high inflammatory cell infiltration rate higher granulation tissue | [36] |
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8 | Propolis extract | Tooth pulp wound | Dentin tubules are arranged more orderly as pulp capping agent | [37] |
9 | Skin wound | Staphylococcus aureus and Staphylococcus epidermidis have inhibitory effects improve skin antibacterial effect | [38] |
10 | Damage caused by striking | Contains fibroblasts and collagen a large number of mitotic cells stimulate cell proliferation and tissue repair | [39] |
11 | Wound (about 11 mm) | Accelerate wound healing improve collagen deposition | [40] |
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12 | Wound dressing containing propolis | Third degree burn wound | The area of the burn was reduced no inflammation and edema | [41] |
13 | Back incision | Fibroblast proliferation contributes to collagen deposition increased synthesis of natural hyaluronic acid | [42] |
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14 | Propolis contains biocellulose membrane | Back and neck trauma | Wound healing improved fibroblast and collagen production increased | [43] |
15 | Wound (about 6 mm) | Tissue repair of contaminated wounds shorter time and better effect | [44] |
16 | Propolis and metal nanoparticles and biology medical thread combination | Surgically infected wound | Promote cell migration and proliferation gives effective antibacterial power to surgical sutures | [45] |
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