Role of Bile Acids and Nuclear Receptors in Acupuncture in Improving Crohn’s Disease

Figure 2

The general structure of nuclear receptors (a) and typical NR dimer (b). The main replication methods of NRs include direct repeat (DR), everted repeat (ER), and inverted repeat (IR). Nt: N-terminal; Ct: C-terminal; AF-1: activation domain 1; DBD: DNA-binding domain; AF-2: transcriptional activation domain; LBD: ligand-binding domain; and RXR: retinoid X receptor.

(a)

(b)