Uncovering the Mechanism of the Xingnaojing Injection against Ischemic Stroke Using a Combined Network Pharmacology Approach and Gut Microbiota Analysis

Table 4

The 7 groups and their interventions.

Group	Abbreviation	n	Intervention	Processing time	Surgical approach
Normal group	NG	6	Normal saline injection	5 days	No surgery
Sham surgery group	SG	12	Normal saline injection	5 days	Isolation of the artery with no occlusion
tMCAO group (control group)	CG	24	Normal saline injection	5 days	tMCAO
Experiment group	EG	24	XNJ (10 ml XNJ and 20 ml normal saline)	5 days	tMCAO
Sham germ-free normal group	SGFNG	6	Normal saline injection	5 days	No surgery
Sham germ-free control group	SGFCG	24	Normal saline injection	5 days	tMCAO
Sham germ-free experiment group	SGFEG	24	XNJ (10 ml XNJ and 20 ml normal saline)	5 days	tMCAO

Notes. The mice were injected abdominally once a day for 5 days (156 ul/10 g), from 2 days before modeling to 3 days after modeling.