Research Article

Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn

Table 6

The sedative effect of crude extracts and various fractions of P. hysterophorus.

TreatmentDoseNo. of lines crossed

Normal saline10 ml/kg126 ± 1.25
Diazepam0.5 mg/kg6 ± 0.13

MeOH25110.51 ± 4.23
50102.60 ± 3.44
10094.68 ± 3.35

Hexane25115.90 ± 4.21
50108.69 ± 3.40
100100.99 ± 3.30

Aqueous2598.51 ± 4.29
5088.63 ± 3.24
10080.61 ± 3.14

Ethyl acetate25107.51 ± 3.99
5097.61 ± 3.29
10089.66 ± 3.00

Chloroform25105.55 ± 4.34
5094.65 ± 3.20
10083.69 ± 3.10

Butanol25100.54 ± 4.200
5090.69 ± 3.23
10081.65 ± 3.13

where, , , and .