Research Article
Phytochemical Analysis and In Vitro and In Vivo Pharmacological Evaluation of Parthenium hysterophorus Linn
Table 6
The sedative effect of crude extracts and various fractions of P. hysterophorus.
| Treatment | Dose | No. of lines crossed |
| Normal saline | 10 ml/kg | 126 ± 1.25 | Diazepam | 0.5 mg/kg | 6 ± 0.13 |
| MeOH | 25 | 110.51 ± 4.23 | 50 | 102.60 ± 3.44 | 100 | 94.68 ± 3.35 |
| Hexane | 25 | 115.90 ± 4.21 | 50 | 108.69 ± 3.40 | 100 | 100.99 ± 3.30 |
| Aqueous | 25 | 98.51 ± 4.29 | 50 | 88.63 ± 3.24 | 100 | 80.61 ± 3.14 |
| Ethyl acetate | 25 | 107.51 ± 3.99 | 50 | 97.61 ± 3.29 | 100 | 89.66 ± 3.00 |
| Chloroform | 25 | 105.55 ± 4.34 | 50 | 94.65 ± 3.20 | 100 | 83.69 ± 3.10 |
| Butanol | 25 | 100.54 ± 4.200 | 50 | 90.69 ± 3.23 | 100 | 81.65 ± 3.13 |
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