Research Article

Gastroprotective Effect of Polypeptide-K Isolated from Momordica charantia’s Seeds on Multiple Experimental Gastric Ulcer Models in Rats

Table 3

Antiulcerogenic effect of PPK against indomethacin.

GroupsDose (mg/kg)Total area of lesion (mm2)Inhibition (%)

Indomethacin only-41.33 ± 3.57-
Indomethacin + ranitidine10013.67 ± 3.15 66.92%
Indomethacin + PPK1023.00 ± 3.38 44.35%
Indomethacin + PPK2517.33 ± 3.56 58.07%
Indomethacin + PPK5011.50 ± 2.01 72.18%

Data are expressed as mean ± SEM (n = 6). Significantly different from indomethacin group at or at .