Research Article
Gastroprotective Effect of Polypeptide-K Isolated from Momordica charantia’s Seeds on Multiple Experimental Gastric Ulcer Models in Rats
Table 3
Antiulcerogenic effect of PPK against indomethacin.
| Groups | Dose (mg/kg) | Total area of lesion (mm2) | Inhibition (%) |
| Indomethacin only | - | 41.33 ± 3.57 | - | Indomethacin + ranitidine | 100 | 13.67 ± 3.15 | 66.92% | Indomethacin + PPK | 10 | 23.00 ± 3.38 | 44.35% | Indomethacin + PPK | 25 | 17.33 ± 3.56 | 58.07% | Indomethacin + PPK | 50 | 11.50 ± 2.01 | 72.18% |
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Data are expressed as mean ± SEM ( n = 6). Significantly different from indomethacin group at or at . |