Neuropharmacological and Antidiabetic Potential of Lannea coromandelica (Houtt.) Merr. Leaves Extract: An Experimental Analysis

Table 8

Effects of L. coromandelica leaves extract on alloxan-induced diabetic mice’s blood glucose levels.

Group	Dose (mg/kg)	Blood glucose level (mg/dl)
		Day 0	Day 4	Day 7	Day 10	Day 15
Normal saline	0.3 ml	125.10 ± 2.50	108.10 ± 2.37	107.2 ± 0.48	104.30 ± 3.40	100.8 ± 2.24
Diabetic control	0.3 ml	420.40 ± 3.50	433.10 ± 2.37	439.25 ± 2.40	450.10 ± 2.58	466.20 ± 2.20
Glibenclamide	10	400.10 ± 3.37	377.20 ± 2.51	344.50 ± 2.19	301.70 ± 2.40	255.37 ± 3.10
Methanol extract	200	405.30 ± 3.51	396.15 ± 3.17	382.75 ± 2.40	371.10 ± 2.24	355.15 ± 3.30
Methanol extract	400	396.25 ± 3.57	378.55 ± 2.60	340.50 ± 2.44	318.10 ± 2.24	297.30 ± 3.32

Results are given as Mean ± SEM (n = 5). and , compared to the control group, are significant (one-way ANOVA followed by Dunnett’s test).