Evaluation of In Vivo Wound-Healing and Anti-Inflammatory Activities of Solvent Fractions of Fruits of Argemone mexicana L. (Papaveraceae)

Table 4

Effect of A. mexicana fruit solvent fractions on n period of epithelialization (no. of days) post wound creation in rats.

Test group	Period of epithelialization in days (mean ± S.E.M)
SO	17.83 ± 0.41
MEBO	12.50 ± 0.55^#acdefg
5% EAF	14.33 ± 0.52^#afg
10% EAF	12.67 ± 0.52^#acdefg
5% n-HF	15.33 ± 0.52^#af
10% n-HF	14.17 ± 0.42^#adf
5% n-AF	16.50 ± 0.55^a
10% n-AF	15.83 ± 0.41^af

Values are expressed as mean ± SEM (n = 6 rats in each group) and analyzed by one-way ANOVA followed by post hoc Tuckey’s test; ^acompared with simple ointment; ^bcompared with MEBO ^ccompared with 5% EAF; ^dcompared with 5% n-HF, ^ecompared with 10% n-HF;^fcompared with 5% AF, ^gcompared with 10% AF; w/w = weight by weight; SO = Simple ointment; ; ^# = ; MEBO = moist-exposed burn ointment; EAF, n-HF, and AF are ethyl acetate, n-hexane and aqueous fractions of A. mexicana fruit, respectively. The initial wound area was 250 mm².