Research Article
Ethanol Extract of Sargassum siliquastrum Inhibits Lipopolysaccharide-Induced Nitric Oxide Generation by Downregulating the Nuclear Factor-Kappa B Signaling Pathway
Figure 3
SS extract inhibits LPS-induced proinflammatory cytokine expression and production. (a) Real-time PCR analyses to determine changes in mRNA levels of Il1b, Il6, and Tnf following treatment with the SS extract (SS) in LPS-stimulated RAW 264.7 cells. (b) ELISA to determine changes in the production of IL-6 and TNF-α following treatment with the SS extract in LPS-stimulated RAW 264.7 cells. The bars represent the mean ± standard deviation (SD); ∗: , ∗∗: , and ∗∗∗: by comparison with the indicated group. SS, Sargassum siliquastrum; LPS, lipopolysaccharide.
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