Research Article
In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from Syzygium cumini (L.) Skeels in Mice
Table 1
Toxicological profile of crude extract and various fractions of Syzygium cumini in open-field screening.
| | Treatment | Doses (mg/kg) | Number of died animals/6 | % mortality | Gross behavior changes |
| | Normal saline | 10 ml/kg | 0/6 | — | — |
| | Methanolic extract | 100 | 0/6 | — | — | | 250 | 0/6 | — | — | | 500 | 0/6 | — | Inactive | | 1000 | 0/6 | — | Inactive |
| | Hexane | 100 | 0/6 | — | — | | 250 | 0/6 | — | — | | 500 | 0/6 | — | — | | 1000 | 0/6 | — | — |
| | Chloroform | 100 | 0/6 | — | — | | 250 | 0/6 | — | — | | 500 | 0/6 | — | Inactive | | 1000 | 0/6 | — | Inactive |
| | DCM | 100 | 0/6 | — | — | | 250 | 0/6 | — | Inactive | | 500 | 0/6 | — | Inactive | | 1000 | 0/6 | — | Inactive |
| | Ethyl acetate | 100 | 0/6 | — | — | | 250 | 0/6 | — | Inactive | | 500 | 0/6 | — | Inactive | | 1000 | 0/6 | — | Inactive |
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