Research Article
In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from Syzygium cumini (L.) Skeels in Mice
Table 2
Analgesic potential of crude extract and various fractions of Syzygium cumini.
| Tested samples | Dose (mg/kg) | No. of writhes |
| Normal saline | 10 mL/kg | 61.098 ± 2.00 |
| Diclofenac sodium | 5 | 29.32 ± 2.20 |
| Methanolic extract | 25 | 44.09 ± 1.88 | 50 | 39.34 ± 1.93 | 100 | 34.43 ± 2.19 | 250 | 29.98 ± 2.00 | 500 | 25.09 ± 2.06 |
| n-Hexane | 25 | 62.65 ± 2.65 | 50 | 57.21 ± 2.12 | 100 | 51.32 ± 2.08 | 250 | 45.54 ± 1.90 | 500 | 40.32 ± 1.87 |
| Chloroform | 25 | 53.09 ± 2.12 | 50 | 48.09 ± 3.01 | 100 | 42.09 ± 2.98 | 250 | 36.09 ± 2.06 | 500 | 30.98 ± 2.43 |
| DCM | 25 | 41.34 ± 1.66 | 50 | 35.66 ± 1.76 | 100 | 29.11 ± 2.09 | 250 | 23.09 ± 2.87 | 500 | 18.34 ± 2.08 |
| Ethyl acetate | 25 | 46.09 ± 1.56 | 50 | 39.34 ± 1.32 | 100 | 33.98 ± 1.34 | 250 | 27.98 ± 1.34 | 500 | 22.87 ± 1.76 |
|
|
|