Research Article

In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from Syzygium cumini (L.) Skeels in Mice

Table 3

Muscle relaxant effect of crude and various fractions of S. cumini.

GroupDose (mg/ml)Inclined plan model (%)Traction screening (%)
30 min60 min90 min30 min60 min90 min

Distilled water10 mL/kg0.00.00.00.00.00.0

Diazepam1100100100100100100

Methanolic extract2535.6544.2353.0934.8043.0052.36
5041.5450.9859.2342.4351.1160.32
10045.2154.8763.1244.2153.8764.04
25048.2357.5466.3247.2356.9867.06
50052.0061.2370.9151.8760.0869.98

n-Hexane2512.2220.0329.9811.3019.7630.70
5016.1725.6633.5417.0026.2334.09
10021.2828.2337.1120.3227.0636.60
25024.9833.4341.0923.3730.3240.09
50028.8736.9844.2127.4335.2143.08

Chloroform2530.1139.4348.9429.0138.0647.66
5036.3245.7754.7635.8844.9853.56
10042.1251.4360.7041.5450.3259.54
25047.4356.3265.8346.4355.3264.76
50053.9862.8771.4352.9861.9070.03

DCM2538.0847.5156.0137.5046.7055.91
5044.6553.5762.4345.0054.0163.07
10050.2359.6068.2251.8960.9067.32
25057.4266.6875.1956.8665.0274.00
50064.2173.7682.3463.0172.9881.03

Ethyl acetate2527.4336.2145.4526.7635.0844.14
5033.6042.9851.1232.8641.1650.87
10039.0948.7657.9840.0049.8358.72
25045.4354.2363.0944.8753.9862.43
50051.6660.6569.2250.9459.9868.88