Research Article
In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from Syzygium cumini (L.) Skeels in Mice
Table 4
Sedative effect of crude and various fractions of Syzygium cumini in open-field screening.
| Samples | Dose (mg/ml) | Number of lines crossed |
| Control | 5 ml | 130.00 ± 3.65 |
| Diazepam | 0.5 | 9.23 ± 0.55 |
| Methanolic extract | 25 | 88.32 ± 3.01 | 50 | 82.04 ± 2.79 | 100 | 75.54 ± 2.70 | 250 | 67.09 ± 2.65 | 500 | 60.21 ± 1.40 |
| n-Hexane | 25 | 112.09 ± 2.09 | 50 | 108.32 ± 2.30 | 100 | 101.87 ± 2.44 | 250 | 95.32 ± 2.54 | 500 | 89.01 ± 2.05 |
| Chloroform | 25 | 80.23 ± 2.13 | 50 | 74.98 ± 2.12 | 100 | 68.23 ± 2.30 | 250 | 62.09 ± 2.34 | 500 | 57.12 ± 2.88 |
| DCM | 25 | 43.98 ± 2.11 | 50 | 37.01 ± 2.73 | 100 | 32.32 ± 2.60 | 250 | 26.21 ± 2.43 | 500 | 20.90 ± 2.00 |
| Ethyl acetate | 25 | 75.8 ± 3.00 | 50 | 69.65 ± 2.83 | 100 | 63.87 ± 2.50 | 250 | 57.23 ± 2.12 | 500 | 52.56 ± 1.82 |
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