Research Article

In Vivo Anti-Inflammatory, Analgesic, Muscle Relaxant, and Sedative Activities of Extracts from Syzygium cumini (L.) Skeels in Mice

Table 4

Sedative effect of crude and various fractions of Syzygium cumini in open-field screening.

SamplesDose (mg/ml)Number of lines crossed

Control5 ml130.00 ± 3.65

Diazepam0.59.23 ± 0.55

Methanolic extract2588.32 ± 3.01
5082.04 ± 2.79
10075.54 ± 2.70
25067.09 ± 2.65
50060.21 ± 1.40

n-Hexane25112.09 ± 2.09
50108.32 ± 2.30
100101.87 ± 2.44
25095.32 ± 2.54
50089.01 ± 2.05

Chloroform2580.23 ± 2.13
5074.98 ± 2.12
10068.23 ± 2.30
25062.09 ± 2.34
50057.12 ± 2.88

DCM2543.98 ± 2.11
5037.01 ± 2.73
10032.32 ± 2.60
25026.21 ± 2.43
50020.90 ± 2.00

Ethyl acetate2575.8 ± 3.00
5069.65 ± 2.83
10063.87 ± 2.50
25057.23 ± 2.12
50052.56 ± 1.82

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