Research Article

Chemical Composition and Insecticidal, Antiplasmodial, and Anti-Leishmanial Activity of Capparis spinosa Essential Oil and Its Main Constituents

Table 3

Insecticidal, antiplasmodial, and anti-leishmanial activity of the essential oil of C. spinosa and its main components, methyl isothiocyanate, hexadecanoic acid, and limonene.

DrugInsecticidal activity LC50 (μg/mL)Anti-leishmanial effect IC50 (μg/mL)Antiplasmodial activity IC50 (μg/mL)Cytotoxicity effect CC50 (μg/mL)

C. spinosa essential oil21.6 ± 2.157.4 ± 0.899.1 ± 1.1293.7 ± 4.54
Methyl isothiocyanate30.9 ± 3.1214.5 ± 2.5120.7 ± 2.54216.2 ± 8.65
Hexadecanoic acid41.6 ± 3.6219.6 ± 3.0523.3 ± 3.14199.4 ± 7.58
Limonene35.3 ± 4.2321.3 ± 2.1518.6 ± 2.19221.3 ± 9.87