Patient number Likert scale score of symptoms mean difference and 90% CI 24-hour sputum volume mean difference and 90% CI CAT scores mean difference and 90% CI TCM syndrome scores mean difference and 90% CI Case 1 −0.11 (−0.35, 0.13) 0.320 −10.00 (−26.86, 6.86) 0.225 0.17 (−4.48, 4.81) 0.926 −0.67 (−2.61, 1.28) 0.423 Case 2 0.14 (−0.23, 0.51) 0.389 −1.50 (−3.73, 0.73) 0.188 0.17 (−1.12, 1.45) 0.742 0.67 (−3.58, 4.91) 0.691 Case 3 0.06 (0.26, 0.38) 0.637 −23.33 (−65.76, 19.09) 0.250 1.33 (0.36, 2.31) 0.057 0.00 (−1.69, 1.69) 1.000 Case 4 −0.22 (−0.48, 0.05) 0.137 −4.00 (−16.16, 8.16) 0.438 −1.00 (−7.08, 5.08) 0.678 −2.33 (−7.48, 2.82) 0.317 Case 5 −0.30 (−0.88.0.29) 0.280 −1.67 (−14.54, 11.21) 0.742 1.33 (−2.07, 4.74) 0.371 −3.0 (−8.84, 2.84) 0.272 Case 6 0.35 (−0.89, 1.58) 0.497 1.667 (−8.46, 11.80) 0.678 1.33 (−4.65, 7.31) 0.582 4.00 (−5.39, 13.39) 0.339 Case 7 2.02 (−0.67, 4.71) 0.159 ※ ※ 7.67 (0.065, 15.269) 0.099 7.67 (−0.30, 15.63) 0.107 Case 8 0.13 (−0.76, 1.01) 0.715 ※ ※ 0.50 (−1.73, 2.73) 0.580 0.67 (−1.28, 2.61) 0.423 Case 9 0.19 (−0.40, 0.78) 0.444 7.22 (−19.78, 34.22) 0.517 1.33 (−2.66, 9.99) 0.233 5.00 (−0.84, 10.84) 0.130 Case 11 −0.08 (−1.25, 1.09) 0.859 −1.11 (−50.21, 47.99) 0.953 0.00 (−6.74, 6.74) 1.000 −0.33 (−6.25, 5.59) 0.885 Case 13 −0.11 (−0.27, 0.05) 0.184 0.56 (−7.56, 8.67) 0.860 −2.33 (−5.84, 1.18) 0.192 −1.00 (−5.46, 3.46) 0.580 Case 14 0.05 (−0.96, 1.06) 0.894 −3.33 (−29.09, 22.42) 0.742 −0.33 (−4.58, 3.91) 0.840 0.33 (−1.61, 2.28) 0.667 Case 15 0.03 (−0.34, 0.39) 0.839 −3.89 (−12.92, 5.14) 0.336 −0.67 (−1.64, 0.31) 0.184 0.33 (−2.24, 2.91) 0.742 Case 17 0.40 (−0.80, 1.61) 0.433 −6.11 (−26.44, 14.22) 0.473 0.00 (−7.35, 7.35) 1.000 3.00 (−3.08, 9.08) 0.286 Case 20 0.07 (−0.05, 0.19) 0.237 0.56 (−1.07, 2.18) 0.423 0.67 (−0.31, 1.64) 0.184 0.33 (−0.64, 1.31) 0.423