Review Article
Effect of Honey on Pediatric Radio/Chemotherapy-Induced Oral Mucositis (R/CIOM): A Systematic Review and Meta-Analysis
Table 3
The evidence quality of outcomes assessed according to the GRADE approach.
| | Quality assessment | No. of patients | Effect | Quality | Importance | | No, of studies | Design | Risk of bias | Inconsistency | Indirectness | Imprecision | Other considerations | Recovery time | Control | Outcome | 95% CI |
| | The recovery time | | 4 | Randomized trials | Serious | Serious | No serious indirectness | No serious imprecision | None | 139 | 137 | MD −5.1 | −9.6–0.61 | Low | Important |
| | The occurrence of R/CIOM | | 4 | Randomized trials | No serious risk of bias | No serious inconsistency | No serious indirectness | Serious | None | 127 | 129 | RR 0.19 | 0.12–0.30 | Moderate | Important |
| | The occurrence of grade III and grade IV R/CIOM | | 4 | Randomized trials | No serious risk of bias | No serious inconsistency | No serious indirectness | Serious | None | 127 | 129 | RR 0.18 | 0.18–0.41 | Moderate | Important |
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