Research Article
Elaborate the Mechanism of Ancient Classic Prescriptions (Erzhi Formula) in Reversing GIOP by Network Pharmacology Coupled with Zebrafish Verification
Table 3
Top 10 molecular dockings optimal binding energy.
| | Rank | Proteins and compounds | Mode | Affinity (kcal/mol) | Dist from rmsd | Best mode rmsd |
| | 1 | IL4, wedelolactone | 1 | −7.6 | 0.000 | 0.000 | | 2 | EGF, ursolic acid | 1 | −7.6 | 0.000 | 0.000 | | 3 | IL2, ursolic acid | 1 | −7.5 | 0.000 | 0.000 | | 4 | IL4, acacetin | 1 | −7.3 | 0.000 | 0.000 | | 5 | IL2, beta-sitosterol | 1 | −7.3 | 0.000 | 0.000 | | 6 | IL4, apigenin | 1 | −7.2 | 0.000 | 0.000 | | 7 | IL4, kaempferol | 1 | −7.2 | 0.000 | 0.000 | | 8 | EGF, specnuezhenide | 1 | −7.1 | 0.000 | 0.000 | | 9 | IL4, demethyl wedelolactone | 1 | −7.1 | 0.000 | 0.000 | | 10 | IL4, specnuezhenide | 1 | −7.1 | 0.000 | 0.000 |
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