Promising Health Benefits of Adjuvant Acmella and Zingiber Extracts Combined with Coenzyme Q10 Phytosomes, Supplementation in Chronic Pain Treated with Medical Cannabis: A Prospective and Open-Label Clinical Study

Table 1

Baseline characteristics and main positive effects of supplementation in subjects (70.83%, excluded dropouts) affected by chronic pain of different etiologies.

Subjects	Before supplementation, T0	After 90 days supplementation, T9	Statistical analysis vs. T0
Number	34	34
Sex (male/female)	7/27	7/27
VAS (mean ± S.D.)	4.8 ± 1.9	2.6 ± 1.9
QUID TOT (mean ± S.D.)	0.24 ± 0.16	0.15 ± 0.14
Benefits	—	Sensory, emotional, pain (35.3%)
	—	Sensory, emotional (5.9%)
	—	Sensory (14.7%)
Improvements	—	Pain evaluation, emotional (2.9%)
	—	Emotional (8.8%)
	—	Pain (5.9%)

Results are expressed as mean ± standard deviation (S.D.); —, not applicable. VAS : visual scale assignment; QUID: Italian pain questionnaire. Mean data analysis, Wilcoxon matched-pairs signed rank test.