Vasorelaxant and Antioxidant Effects of <i>Aframomum pruinosum</i> Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction

<div>Oral administration of the aqueous (AE) and ethanolic extracts (EE) of <i>Aframomum pruinosum</i> seeds reduced systolic (SBP), panels (a) and (b) and diastolic blood pressure (DBP), panels (c) and (d) in normal rat. 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103S58 78 58 46C58 11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,49.05,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,55.29,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,61.53,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> statistically different compared to distilled water (DW) or 5% DMSO. Numbers in the legend refer to the dose in mg/kg. Prop: propranolol.</div>

Evidence-Based Complementary and Alternative Medicine

fig1

Figure 1

Figure 1: Vasorelaxant and Antioxidant Effects of <i>Aframomum pruinosum</i> Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction 

Figure 1 | Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction 