Research Article

Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction

Figure 4

Isoproterenol significantly increased heart (panel (a) and left ventricular (panel (b) relative weight that was prevented by pretreatment with the aqueous (AE) and ethanolic extract (EE) of Aframomum pruinosum seeds, administered orally. Animals were treated for two weeks before induction of myocardial infarction with isoproterenol. Data are expressed as mean ± SEM (n = 8–9). statistically different compared to naive. ; ; statistically different compared to ISO. Numbers refer to the dose in mg/kg.
(a)
(b)