Research Article

Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction

Figure 5

The aqueous (AE) and ethanolic extract (EE) of Aframomum pruinosum seeds administered orally prevented the rise in blood lactate dehydrogenase (LDH); panel (a), alanine amino transferase (ALT); panel (b) and aspartate amino transferase (AST); panel (c) following isoproterenol (ISO) induced myocardial infarction. Animals were treated for two weeks before induction of myocardial infarction with isoproterenol. Data are expressed as mean ± SEM (n = 6–8). ; statistically different compared to naive. ; ; statistically different compared to ISO. Numbers refer to the dose in mg/kg.
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