Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction

Figure 7

Aqueous and ethanolic extracts from the seeds of Aframomum pruinosum protected rat heart against isoproterenol-induced myocardial infarction. Pictures present transverse sections of heart apexes of naïve (a) isoproterenol control (b) isoproterenol + captopril (c) isoproterenol + aqueous extract at the dose of 75 mg/kg (d) or 150 mg/kg (e) and isoproterenol + ethanolic extract at the dose of 75 mg/kg (f) or 150 mg/kg (g) Yellow arrows indicate immune cell infiltration, green arrows indicate fibrosis and black arrows indicate cardiomyocyte necrosis. Slices were stained with hematoxylin & eosin. Magnification × 400.