Research Article
Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction
Figure 8
The aqueous (AE) and ethanolic extracts (EE) from Aframomum pruinosum seeds induced concentration-dependent vasorelaxation of thoracic aorta rings precontracted with noradrenaline (panel (a)). The effects of the plant extracts were tested in the presence (+endo) or absence (−endo) of a functional endothelium or Nω-nitro-L-arginine methyl ester (L-NAME); panels (b) and (c). Panel (d) shows the effects of carbachol (Carb) on intact aorta rings and in presence of L-NAME. n = 5–6. ; ; compared to EE + endo or Carb + endo.
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