Evidence-Based Complementary and Alternative Medicine

Research Article

Vasorelaxant and Antioxidant Effects of Aframomum pruinosum Gagnep. (Zingiberaceae) Seed Extracts May Mediate Their Cardioprotective Activity against Isoproterenol-Induced Myocardial Infarction

Table 2

The aqueous (AE) and ethanolic extracts (EE) from Aframomum pruinosum seeds improved the redox status in the heart of rats subjected to isoproterenol (ISO) induced myocardial infarction.
Experimental groupsSOD (U/mg protein)CAT (U/mg protein)MDA (nmole/g tissue)GSH (nmole/g tissue)
Naive19.20 ± 2.0713.67 ± 1.4310.90 ± 2.00981.90 ± 83.37
ISO8.07 ± 0.928.62 ± 0.6624.31 ± 0.92396.80 ± 26.24
Prop + ISO44.97 ± 8.9849.53 ± 9.194.17 ± 0.75844.10 ± 94.94
AE 75 + ISO15.12 ± 1.2812.46 ± 0.914.27 ± 0.561204.00 ± 103.40
AE 150 + ISO28.90 ± 7.8219.08 ± 4.0410.52 ± 2.92800.20 ± 53.26
EE 75 + ISO119.50 ± 30.93107.00 ± 18.869.29 ± 2.46647.80 ± 89.23
EE 150 + ISO42.02 ± 12.3235.49 ± 7.996.55 ± 1.87737.30 ± 37.37
Data are expressed as mean ± SEM (n = 5–6). ; statistically different compared to naive. ; ; statistically different compared to ISO. Numbers refer to the dose in mg/kg.