A Network Meta-Analysis of the Clinical Efficacy and Safety of Commonly Used Chinese Patent Medicines in the Auxiliary Treatment of Poststroke Depression

Table 1

Basic information included in the study.

Included study	Cases (T/C)	Age	Intervention measures		Course of treatment (d)	Outcome indicators
			Test group (T)	Control group (C)
Han xuqing 2014 [18]	28/30	59.29 ± 10.4	Wuling capsules 2 capsules, bid + Citalopram 10 mg/d, qd	Citalopram 10 mg/d, qd	24	①②
Wu yuhong 2013[19]	35/35	55∼77	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, bid	Dealixin 1 tablet, bid	56	①②
Guo ying 2013[20]	95/95	68.14 ± 7.62	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, bid	Dealixin 1 tablet, bid	42	①②③④
Mo shaozhen 2015[21]	69/69	45∼75	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, tid	Dealixin 1 tablet, tid	42	①②
Ma yunzhi 2012 [22]	30/30	64.8 ± 9.3	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, tid	Dealixin 1 tablet, tid	42	①②③④
Zhou hongye 2015 [23]	34/32	47∼74	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, tid	Dealixin 1 tablet, tid	84	①⑤
Chen liang 2015 [24]	34/34	46∼75	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, tid	Dealixin 1 tablet, tid	42	①②
Zhang lili 2010 [25]	45/45	45∼74	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, tid	Dealixin 1 tablet, tid	42	①②
Liang yuan 2014 [26]	30/30	55.12 ± 5.2	Wuling capsules 3 capsules, tid + Dealixin 1 tablet, tid	Dealixin 1 tablet, tid	42	①②
Zhang danni 2016 [27]	50/50	52∼77	Wuling capsules 3 capsules, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	42	①②
Ma binfeng 2017 [28]	63/63	58∼86	Wuling capsules 3 capsules, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②
Shi qi 2008 [29]	30/26	46∼82	Wuling capsules 3 capsules, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	42	①②
Kou jianhua 2019 [30]	40/40	42∼75	Wuling capsules 3 capsules, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	84	①②④
Kong xiangfang 2014 [31]	38/38	43∼76	Wuling capsules 3 capsules, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②④
Yuan jun 2014 [32]	85/85	45∼75	Wuling capsules 3 capsules, tid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	28	①②④
Wan ailan 2006 [33]	35/35	59.23 ± 8.3	Wuling capsules 3 capsules, tid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	42	①②
Liu junqiong 2014 [34]	32/32	52∼78	Wuling capsules 3 capsules, tid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	56	①②
Xie yan 2018 [35]	49/49	52∼78	Wuling capsules 3 capsules, tid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	56	①②③④
Zhou peng 2017 [36]	34/34	18∼68	Xiaoyao pill 8 pills, tid + Venlafaxine 75 mg/d, qd	Venlafaxine 75 mg/d, qd	28	①②
Wang jianqiang 2014 [37]	60/52	45∼75	Xiaoyao pill 8 pills, tid + Deanxit 1 tablet, bid	Deanxit 1 tablet, bid	42	①②③
Zou lihua 2009 [38]	30/30	67.9 ± 6.1	Xiaoyao pill 8 pills, tid + Deanxit 1 tablet, bid	Deanxit 1 tablet, bid	42	①②
Ceng miaolin 2018 [39]	43/43	33∼79	Xiaoyao pill 8 pills, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	28	①②
Jiang limin 2019 [40]	74/74	36∼76	Danzhi Xiaoyao powder 3 g/d, bid + Citalopram 10 mg/d, qd	Citalopram 10 mg/d, qd	28	①②
Xu erping 2006 [41]	35/35	55.2 ± 1.9	Danzhi Xiaoyao powder 6 g/d, bid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②
Wang zongyuan 2008 [42]	36/36	55∼79	Danzhi Xiaoyao powder 6 g/d, bid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	84	①②
Zhang yumao 2014 [43]	40/40	47∼73	Danzhi Xiaoyao powder 6 g/d, bid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	56	①②③
Peng xianwen 2014 [44]	49/49	45∼78	Danzhi Xiaoyao powder 6 g/d, bid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	28	①②
Cui yi 2016 [45]	30/30	45∼80	Chaihu Shugan powder granules + citalopram 10 mg/d, qd	Citalopram 10 mg/d, qd	42	①②④
Wen jun 2015 [46]	60/60	50∼83	Shugan Jieyu capsule 2 capsules, bid + Mirtazapine 30 mg/d, qd	Mirtazapine 30 mg/d, qd	42	①②③④
Chen aijun 2013 [47]	39/39	49∼78	Shugan Jieyu capsule 2 capsules, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	42	①③
Hou jihong 2015 [48]	36/36	69.3 ± 7.5	Shugan Jieyu capsule 2 capsules, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	56	①②
Wu hongyi 2015 [49]	40/40	50∼65	Shugan Jieyu capsule 2 capsules, bid + Deanxit 1 tablet, qd	Deanxit 1 tablet, qd	28	①②
Zhao zheng 2013 [50]	40/40	43∼75	Shugan Jieyu capsule 2 capsules, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	42	①②
Ding na 2014 [51]	40/40	56.42 ± 5.18	Shugan Jieyu capsule 2 capsules, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	56	①②
Na wanqiu 2012 [52]	41/39	71.12 ± 5.51	Shugan Jieyu capsule 2 capsules, bid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	56	①②③
Hu jun 2013 [53]	45/44	56.42 ± 5.18	Shugan Jieyu capsule 2 capsules, bid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	42	①②
Tan hongyang 2018 [54]	62/62	52∼73	Shugan Jieyu capsule 2 capsules, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	21	①②③④
Lu yi 2015 [55]	65/65	45∼72	Shugan Jieyu capsule 2 capsules, bid + Olanzapine 2.5 mg/d, qd	Olanzapine 2.5 mg/d, qd	56	①②
Xu ming 2012 [56]	65/65	55∼74	Shugan Jieyu capsule 2 capsules, bid + Venlafaxine 75 mg/d, bid	Venlafaxine 75 mg/d, bid	42	①②
Liu wei 2016 [57]	38/38	50∼75	Shugan Jieyu capsule 2 capsule, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	56	①②③
Chen wei 2014 [58]	58/57	45∼73	Shugan Jieyu capsule 2 capsules, bid + Venlafaxine 75 mg/d, bid	Venlafaxine 75 mg/d, bid	42	①③
Yi kunchang 2018 [59]	48/48	48∼77	Shugan Jieyu capsule 2 capsules, bid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	56	①②
Pan zhenshan 2014 [60]	42/42	65.12 ± 8.35	Shugan Jieyu capsule 2 capsules, bid + Mirtazapine 30 mg/d, qd	Mirtazapine 30 mg/d, qd	56	①②③
Li junling 2013 [61]	27/27	49∼75	Shugan Jieyu capsule 2 capsules, bid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②
Xie yan 2017 [62]	45/45	55∼70	Jieyu Anshen granules 5 g, bid + Deanxit 1 pill, qd	Deanxit 1 pill, qd	42	①②
Xia junbo 2013 [63]	40/40	34∼72	Jieyu Anshen granules 5 g, bid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②
Mu ying 2014 [64]	48/48	40∼78	Yangxue Qingnao granules 4 g/d, tid + Paroxetine 20 mg/d, qd	Paroxetine 20 mg/d, qd	28	①④
Jiang guohua 2018 [65]	60/60	60∼77	Yangxue Qingnao granules 4 g/d, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②③④
Huang xiaohong 2012 [66]	50/50	61.5 ± 7.8	Yangxue Qingnao granules 4 g/d, tid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	56	①②
Pan dong 2014 [67]	38/41	60∼75	Yangxue Qingnao granules 4 g/d, tid + Sertraline 50 mg/d, qd	Sertraline 50 mg/d, qd	56	①②
Ceng zhaofu 2013 [68]	34/34	41∼75	Yangxue Qingnao granules 4 g/d, tid + Fluoxetine 20 mg/d, qd	Fluoxetine 20 mg/d, qd	56	①②
Wang xuejun 2017 [69]	32/32	61.37 ± 6.26	Yangxue Qingnao granules 4 g/d, tid + Citalopram 10 mg/d, qd	Citalopram 10 mg/d, qd	42	①②③

① Total effective rate; ② HAMD score (Hamilton Depression Scale); ③ TESS total score (adverse reactions); ④ NIHSS score (neurological deficit score). The intervention measures were based on the routine treatment of stroke..