Evidence-Based Complementary and Alternative Medicine

Research Article

Investigating the Molecular Mechanism of Quercetin Protecting against Podocyte Injury to Attenuate Diabetic Nephropathy through Network Pharmacology, MicroarrayData Analysis, and Molecular Docking

Table 2

KEGG (A) and GO (B) term enrichment results from ClueGO.
IDDescriptionPercentageCount
A
 KEGG: 04933AGE-RAGE signaling pathway in diabetic complications94.44%36
 KEGG: 05418Fluid shear stress and atherosclerosis1.39%15
 KEGG: 04610Complement and coagulation cascades1.39%4
 KEGG: 05014Amyotrophic lateral sclerosis (ALS)1.39%3
 KEGG: 04923Regulation of lipolysis in adipocytes1.39%3
B
 GO: 1903409Reactive oxygen species biosynthetic process36.92%18
 GO: 0001937Positive regulation of endothelial cell proliferation26.92%24
 GO: 0048662Positive regulation of smooth muscle cell proliferation12.31%20
 GO: 0001936Regulation of endothelial cell proliferation8.84%17
 GO: 2000377Regulation of reactive oxygen species metabolic process5.34%31
 GO: 0014074Response to purine-containing compound5.34%17
 GO: 0045766Positive regulation of angiogenesis2%17
 GO: 0007589Body fluid secretion2%6
 GO: 0042730Fibrinolysis2%5
 GO: 0001937Negative regulation of endothelial cell proliferation2%3