Network Pharmacology and Molecular Docking Analysis of the Mechanism Underlying Yikunyin’s Therapeutic Effect on Menopausal Syndrome

Figure 7

“Molecular docking 3D diagram. Small drug molecules are represented by sky blue sticks, hydrogen bonds by yellow dotted lines, and amino acid residues bound to small drug molecules by green sticks. (a) Paeoniflorin-AKT1 (binding energy = −8.35 kcal·mol-1). (b) Luteolin-AKT1 (binding energy = −8.61 kcal·mol-1). (c) Beta-sitosterol-AKT1 (binding energy = −10.09 kcal·mol-1). (d) Kaempferol-AKT1 (binding energy = −7.38 kcal·mol-1). (e) Quercetin-AKT1 (binding energy = −7.24 kcal·mol-1). (f) Beta-sitosterol-IL-6 (binding energy = −8.9 kcal·mol-1). (g) Kaempferol-IL-6 (binding energy = −8.17 kcal·mol-1). (h) Luteolin-IL-6 (binding energy = −7.34 kcal·mol-1). (i) Paeoniflorin-IL-6 (binding energy = −14.76 kcal·mol-1). (j) Quercetin-IL-6 (binding energy = −8.0 kcal·mol-1)”.

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