Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition

<div>(a) Single-cell subpopulation classification of fibroblasts via the tSNE diagram. Each dot represents a cell. Left image: different colours indicate fibroblasts; right image: different colours indicate different subgroups of fibroblasts. (b) Statistical histogram of the number of upregulated genes in each subgroup. (c) Heat map of marker gene expression in various fibroblast subgroups. Genes with upregulated expression showing the top 10 fold changes in each cluster were selected for heat map construction. Colour indicates the level of the corresponding gene expression in the cell.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition 

Figure 3 | Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition 