Single-Cell RNA-Sequencing Reveals the Cellular and Genetic Heterogeneity of Skin Scar to Verify the Therapeutic Effects and Mechanism of Action of Dispel-Scar Ointment in Hypertrophic Scar Inhibition

Figure 4

(a)–(d) Differentially expressed genes and volcano maps. Left images: the abscissa and the ordinate represent the treatment and control groups, respectively. The red points represent genes that are significantly differentially expressed between the two groups, and the grey points represent genes that are not significantly differentially expressed between the two groups. The top 10 genes with the largest differential upregulation/downregulation of expression are labelled. Right images: blue indicates genes whose expression is differentially downregulated in the treatment group compared with that in the control group; red indicates genes whose expression is differentially upregulated in the treatment group compared with that in the control group; and grey indicates genes that were not significantly different.

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